The use of HeberFERON in patients with basal-cell carcinoma treated in the municipality of Puerto Padre, Las Tunas
Keywords:
BASAL CELL CARCINOMA, SKIN NEOPLASMS, THERAPEUTICS.Abstract
Background: Basal-cell carcinoma can be treated with different methods, depending on the clinical variant, location and size of the lesion. There is a history of the successful use of HeberFERON as a therapeutic alternative for this type of carcinoma.
Objective: to assess the effectiveness of HeberFERON in patients with basal-cell carcinoma who visited the dermatology department of the “Guillermo Domínguez López” General Teaching Hospital of Puerto Padre, Las Tunas, from October 2017 to April 2018.
Methods: an observational, descriptive, cross-sectional study was carried out with 9 patients diagnosed with basal-cell carcinoma, treated at the aforementioned institution and during the period herein declared. The histological type of the tumor was identified. The patients were administered the medication by perilesional infiltration or intramuscular injection, according to the size of the tumor, number of lesions and the grade of the actual actinic damage.
Results: 33,3 % of the patients presented basal-cell carcinoma of the nodular subtype and an equal number presented the squamous subtype. Six patients (66,7 %) received treatment through perilesional infiltration. A total cure in five patients (55,6 %) was achieved, three had a partial healing and one had to be interrupted due to adverse reactions. All the patients showed general secondary reactions to treatment as fever, general malaise, fatigue and arthralgia.
Conclusions: HeberFERON proved to be effective for the treatment of basal-cell carcinoma in the studied patients, mainly for those with not much actinic damage and only one lesion.
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