Characterization of patients with bacterial meningoencephalitis admitted to the intensive care unit of a general hospital
Keywords:
CENTRAL NERVOUS SYSTEM, MENINGOENCEPHALITIS, PROGNOSISAbstract
Background: bacterial meningoencephalitis is an important cause of morbidity and mortality at worldwide level. The sudden onset of its symptomatology, the fatal end in a few hours and the permanence of sequels make it have a great social impact.
Objective: to characterize the patients with a diagnosis of bacterial meningoencephalitis admitted to the intensive care unit of the “Dr. Ernesto Guevara de la Serna” Hospital of Las Tunas, during the years 2017 and 2018.
Methods: an observational descriptive cross-sectional study was carried out with a sample of 53 patients with the criteria defined in the objective and with a medical history including all the data needed for the research. The following variables were assessed: age, sex, factors of a bad prognosis, complications and status at discharge.
Results: the illness prevailed in the age group of 60 years and older with 43,4 %, this being the main factor of a bad prognosis. It was slightly more frequent in the male sex. According to the status at discharge 13,2 % of the patients died. Among the infectious biological agents most frequently identified was the Streptococcus pneumoniae in 73,5 %. Out of the totality of the patients, 52,8 % suffered from some complication, with a discreet prevalence of neurological ones.
Conclusions: the patients with bacterial meningoencephalitis were characterized, mostly with Streptococcus pneumoniae, and with advanced age as the main factor for a bad prognosis.
Downloads
References
Cobian-Caballero CO, Romero-García LI, Laguna-Delisle M, Filiú-Ferrera JL. Aspectos epidemiológicos, clínicos, terapéuticos y evolutivos de la meningoencefalitis bacteriana. MediSan. [revista en internet] 2016 Jul [citado 8 de enero 2020]; 20(7): 912-920. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=66883.
García-Gómez A, Amador-Carpio M, Pradere-Pensado JC, Nistal-Mena J, Gutiérrez- Gutiérrez L. Pacientes con infección del sistema nervioso central. Rev Cub Med Mil [revista en internet] 2015 [citado 8 de enero 2020]; 44(1): 11–23. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572015000100003&lng=es.
Jiménez-Martínez MC, Padilla-Docal Bárbara, Cisneros-Hechavarría VM. Tratamiento antimicrobiano en la meningoencefalitis, Hospital Militar Central "Dr. Luis Díaz Soto", 2004-2011. Rev Cubana Farm [revista en internet]. 2014 [citado 8 de enero 2020]; 48(1): 34-42. Disponible en: https://www.medigraphic.com/pdfs/revcubfar/rcf-2014/rcf141e.pdf.
Charry JD, García FA, Ortega NJ, Osorio J. Infecciones del sistema nervioso central en pacientes críticos con lesión cerebral, con y sin antecedente de manejo neuroquirúrgicos. Acta Colomb Cuid Intensivo. [revista en internet] 2015 [citado 8 de enero 2020]; 15(1): 9-12 Disponible en: https://www.clinicalkey.es/#!/content/journal/1-s2.0-S0122726215000105.
Tena-Suck ML. Líquido cefalorraquídeo. Patología Revista Latinoamericana [revista en internet]. 2018 [citado 8 de enero 2020]; 56(4): 281–87. Disponible en: http://www.revistapatologia.com/content/250319/2018-4/9-IF-Li_quido.pdf.
Figueiras-Ramos B, Romero-Cabrera Á, López-Fernández R, Borroto-Lecuona S, Nieto-Cabrera R. Caracterización de pacientes con infecciones del sistema nervioso central. Medisur [revista en internet]. 2011 [citado 8 de enero 2020]; 9(3): [aprox. 12 p]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/1124.
Valle-Murillo MA, Amparo-Carrillo ME. Infecciones del Sistema Nervioso Central, parte 1: Meningitis, Encefalitis y Absceso cerebral. Rev Mex Neuroci. [serie en Internet] 2017 [citado 10 de enero 2020]; 18(2): 51-65. Disponible en: https://www.medigraphic.com/pdfs/revmexneu/rmn-2017/rmn172f.pdf.
Naderi H, Sheybani F, Khosravi O, Jabbari Nooghabi M. Frequency of Different Types of Diagnostic Errors in Patients with Central Nervous System Infections: A Cross-Sectional Observational Study. Hindawi.
Neurology Research International [revista en internet] 2018 [citado 10 de enero 2020]; 1–7. Disponible en: https://doi.org/10.1155/2018/4210737.
Lahiri Mukhopadhyay S, Bahubali VH, Manjunath N, Swaminathan A, Maji S, Palaniappan M, et al. Central nervous system infection due to Cryptococcus gattiisensulato in India: Analysis of clinical features, molecular profile and antifungal susceptibility. Mycoses. [revista en internet] 2017 [citado 10 de enero 2020]; 60(11): 749–757. Disponible en: https://doi.org/10.1111/myc.12656.
García S, Sauri-Suárez S, Meza E, Arrazola-Cortés E, Sevilla-Álvarez C, de Jesús Villa-Gómez AJ. Procesos infecciosos del sistema nervioso central en el preludio del siglo XXI; una revisión analítica. Med Int Mex. [revista en internet] 2013, [citado 10 de enero 2020]; 29(3): 276-289. Disponible en: https://www.medigraphic.com/pdfs/medintmex/mim-2013/mim133h.pdf.
Ramírez-Calderón F, Sotelo-Jiménez P, Rodriguez-Malaver C. Atypical presentation for bacterial meningitis in an elderly woman: report of a case. Acta méd. Peru [revista en internet] 2019 [citado 10 de enero 2020]; 36(1): 62-67. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1728-59172019000100010&lng=es.
Peña-Aldana A, García-Álvarez JA, Martínez-Hermida M, Ruiz-Juan Y, preval-Campello N. Meningoencefalitis bacteriana, estudio de algunos factores. Revista de Información Científica [revista en internet] 2017 [citado 10 de enero 2020]; 96(5): 883–91. Disponible en: https://www.medigraphic.com/pdfs/revinfcie/ric-2017/ric175j.pdf.
Horcajada JP. Aplicabilidad de los parámetros PK/PD de los antimicrobianos en el tratamiento de infecciones complejas y resistencias extremas. Rev Esp Quimioter [revista en internet] 2015 [citado 10 de enero 2020]; 28(Suppl. 1): 16-18. Disponible en: http://www.seq.es/seq/0214-3429/28/sup1/horcajada.pdf.
Nuvials X, Arnau E, Serra J, Alcaraz R, Larrosa-Escartín MN, Palomar-Martínez M, et al. Influencia de la confirmación microbiológica en la duración y adaptación del tratamiento antimicrobiano empírico de los pacientes ingresados en UCI. Rev Esp Quimioter [revista en internet] 2014 [citado 10 de enero 2020]; 27(4): 252-260. Disponible en: https://seq.es/wp-content/uploads/2014/12/seq.es_seq_0214-3429_27_4_nuvials.pdf.
Cabrera-Maqueda JM, Fuentes-Rumí L, Valero-López G, Baidez-Guerrero AE, García-Molina E, Díaz-Pérez J, et al. Difusión de los antibióticos en el sistema nervioso central. Rev Esp Quimioter [revista en internet] 2018 [citado 11 de enero 2020]; 31(1): 01-12. Disponible en: https://seq.es/wp-content/uploads/2018/02/cabrera31jan2018.pdf.
Morales-Cartagena A, Lalueza A, San Juan R, Aguado J. Staphylococcusaureus sensible a cloxacilina con CMI elevada a glucopéptidos. ¿Ponemos siempre cloxacilina? Rev Esp Quimioter [revista en internet] 2015 [citado 11 de enero 2020]; 28 (Suppl. 1): 25-29. Disponible en: http://web.a.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=1&sid=da501ada-299b-40cb-9fe7-247b4e79fa04%40sessionmgr4008.
Downloads
Published
How to Cite
Issue
Section
License
This journal provides free and immediate access to its content under the principle that making research freely available to the public supports a greater exchange of global knowledge. This means that the authors transfer the copyright to the journal, so that copies and distribution of the contents can be made by any means, as long as the authors' acknowledgment is maintained. These terms are a reflection that the journal assumes copyright under Creative Commons licenses, specifically under a Creative Commons Attribution 4.0 International license.
Registration and submission of articles to the journal is free. The processing, including review, editing and publication, is completely free of charge.